名稱 | EDNRB/β-Arrestin/CHO GPCR細(xì)胞 |
型號 | CBP71376 |
報(bào)價(jià) | |
特點(diǎn) | EDNRB/β-Arrestin/CHO |
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聯(lián)系人:蔣經(jīng)理
電話:4008750250
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > GPCR細(xì)胞株 > CBP71376EDNRB/β-Arrestin/CHO GPCR細(xì)胞
- 詳細(xì)內(nèi)容
CBP71376 | |
I. Background | |
EDNRB (Endothelin Receptor Type B) is a Protein Coding gene. Diseases associated with EDNRB include Waardenburg Syndrome, Type 4A and Abcd Syndrome. Among its related pathways are Class A/1 (Rhodopsin-like receptors) and Endothelins. Gene Ontology (GO) annotations related to this gene include G protein-coupled receptor activity and type 1 angiotensin receptor binding. | |
II. Introduction | |
Host Cell: | CHO |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | F12K+10%FBS+5ug/ml puromycin+5ug/ml blasticidin |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assay for EDNRB receptor |
Transducer: | Activation of ETB receptors to produce a range of biological actions in different tissues is thought to be mediated by a number of transduction systems coupled to various types of G-protein including Gq/G11, Gs, Gq/13 and Gi2. |
Ⅲ. Description of Host Cell Line | |
Organism: | Hamster |
Tissue: | Ovary |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data | |
Figure 1.Recombinant EDNRB/β-Arrestin/CHO constitutively expressing EDNRB/β-Arrestin. | |
Figure 2. Dose response of Endothelin 3 (human,mouse,rabbit, rat TFA) in CHO-K1 EDNRB(ET2,ETB) β-Arrestin Cell line(C11). |