名稱 | AI-Edigene® NRAS p.G12A Reference Standard Pl |
型號 | CBP10526 |
報價 | |
特點 | AI-Edigene® NRAS p.G12A Reference Standard Plus |
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聯(lián)系人:蔣經(jīng)理
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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- 詳細內(nèi)容
CBP10526 | |
Format | Genomic DNA |
Description | NRAS G12A is hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12A has not been characterized, but can be predicted to confer a loss of function on Nras protein based on the effects of HRAS G12A and KRAS G12A, which results in decreased GTPase activity, loss of response to GTPase-activating proteins, and transformation of cultured cells (PMID: 6092966, PMID: 26037647). |
Technical Data | |
DNA Change: | c.35G>C |
AA Change | p.G12A |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | NM_002524.5 |
Cosmic ID | COSM565 |
Chr position(GRCh37) | chr1:115258747 |
Buffer: | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purity | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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