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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10517AI-Edigene® PIK3CA p.E545K Reference Standard

AI-Edigene® PIK3CA p.E545K Reference Standard
名稱 AI-Edigene® PIK3CA p.E545K Reference Standard
型號(hào) CBP10517
報(bào)價(jià)
特點(diǎn) AI-Edigene® PIK3CA p.E545K Reference Standard Plus
  • 詳細(xì)內(nèi)容
 CBP10517
FormatGenomic DNA
DescriptionPIK3CA E545K is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545K results in increased phosphorylation of Akt and Mek1/2, growth factor-independent cell survival, and is transforming in culture (PMID: 26627007, PMID: 29533785).
  
Technical Data 
DNA Changec.1633G>A
AA Changep.E545K
Mutation typeSubstitution - Missense
ZygosityHomozygous
Allelic Frequency100.00%
TranscriptNM_006218.4
Cosmic IDCOSM763
Chr position(GRCh37)chr3:178936091
BufferTris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10517.png

Storage4°C
Expiry36 months from the date of manufacture

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