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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10540CHEK1 p.L355* Reference Standard 標(biāo)準(zhǔn)品

CHEK1 p.L355* Reference Standard 標(biāo)準(zhǔn)品
名稱 CHEK1 p.L355* Reference Standard 標(biāo)準(zhǔn)品
型號 CBP10540
報(bào)價(jià)
特點(diǎn) CHEK1 p.L355* Reference Standard
  • 詳細(xì)內(nèi)容
 CBP10540
FormatGenomic DNA
DescriptionCHEK1, checkpoint kinase 1, is a serine/threonine kinase activated in response to DNA damage that is responsible for mediating checkpoint signaling from ATM and ATR (PMID: 23613359, PMID: 12781359). Overexpression of Chek1 has been observed in several tumor types, including gastric cancer, small cell lung cancer, T-cell leukemia (PMID: 25132270, PMID: 26867682, PMID: 28490518), and breast cancer (PMID: 31933717).
  
Technical Data 
DNA Change:c.1064delT
AA Changep.L355*
Mutation typeFrame_Shift_Del
ZygosityHeterozygous
Allelic Frequency50%
TranscriptNM_001274.5
Cosmic IDN/A
Chr position(GRCh37)chr11:125514126
Buffer:Tris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

10540.png

Storage4℃
Expiry36 months from the date of manufacture

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