名稱 | FGFR3 p.V89fs Reference Standard 標準品 |
型號 | CBP10503 |
報價 | |
特點 | FGFR3 p.V89fs Reference Standard |
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聯(lián)系人:蔣經(jīng)理
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
- 詳細內容
CBP10503 | |
Format | Genomic DNA |
Description | FGFR3, fibroblast growth factor receptor 3, is a receptor tyrosine kinase activated upon binding of the FGF ligand, which activates RAS-MAPK and PI3K-AKT pathways (PMID: 22508544). Altered function of FGFR3 in cancer may lead to increased cell proliferation and decreased apoptosis (PMID: 22508544) and mutations and fusions are commonly observed in bladder cancer (PMID: 30975452, PMID: 23175443). |
Technical Data | |
DNA Change | c.267delG |
AA Change | p.V89fs |
Mutation type | Frame_Shift_Del |
Zygosity | Heterozygous |
Allelic Frequency | 50% |
Transcript | ENST00000481110.2 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr4:1801138 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |