名稱 | HRAS p.G12D Reference Standard |
型號 | CBP10288 |
報價 | |
特點 | HRAS p.G12D Reference Standard |
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電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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CBP10288 | |
Format | Genomic DNA |
Description | HRAS G12D is hotspot mutation that lies within the GTP binding domain of the Hras protein (UniProt.org). G12D results in decreased Hras GTPase activity, loss of sensitivity to GTPase-activating proteins, thus leads to transformation of cells in culture (PMID: 24224811, PMID: 6092966). |
Technical Data | |
DNA Change | c.35G>A |
AA Change | p.G12D |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000397596 |
Cosmic ID | COSM484 |
Chr position(GRCh37) | chr11:534288 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |