名稱 | KRAS p.G12D Reference Standard 標(biāo)準(zhǔn)品 |
型號 | CBP10292 |
報價 | |
特點(diǎn) | KRAS p.G12D Reference Standard |
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10292KRAS p.G12D Reference Standard 標(biāo)準(zhǔn)品
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CBP10292 | |
Format | Genomic DNA |
Description | KRAS G12D is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12D results in decreased Kras GTPase activity and increased activation of downstream signaling, promotes tumor formation in mouse models (PMID: 16474405, PMID: 26037647, PMID: 22871572) and is transforming in cell culture (PMID: 29533785). |
Technical Data | |
DNA Change | c.35G>A |
AA Change | p.G12D |
Mutation type | Substitution - Missense |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000311936 |
Cosmic ID | COSM521 |
Chr position(GRCh37) | chr12:25398284 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |