名稱 | KRAS p.G13C Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10299# |
報(bào)價(jià) | |
特點(diǎn) | KRAS p.G13C Reference Standard |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10299#KRAS p.G13C Reference Standard 標(biāo)準(zhǔn)品
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CBP10299# | |
Format | Genomic DNA |
Description | KRAS G13C is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G13C results in decreased Kras GTPase activity, as indicated by increased Ras-GTP, and leads to activation of downstream signaling in cell culture (PMID: 25705018, PMID: 21079152). |
Technical Data | |
DNA Change | c.37G>T |
AA Change | p.G13C |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000311936 |
Cosmic ID | COSM527 |
Chr position(GRCh37) | chr12:25398282 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |