名稱 | TP53 p.K319* Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10531 |
報(bào)價(jià) | |
特點(diǎn) | TP53 p.K319* Reference Standard |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10531TP53 p.K319* Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10531 | |
Format | Genomic DNA |
Description | TP53, tumor protein p53, is a tumor suppressor (PMID: 30562755) and oncogene (PMID: 30577483) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457). |
Technical Data | |
DNA Change | c.955A>T |
AA Change | p.K319* |
Mutation type | Nonsense_Mutation |
Zygosity | Homozygous |
Allelic Frequency | 100% |
Transcript | ENST00000269305.4 |
Cosmic ID | COSM11658 |
Chr position(GRCh37) | chr17:7576891 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4°C |
Expiry | 36 months from the date of manufacture |