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基因檢測標準品 > 用藥指導 > CBPA0072CYP2D6*10 Reference Standard

CYP2D6*10 Reference Standard
名稱 CYP2D6*10 Reference Standard
型號 CBPA0072
報價
特點 CYP2D6*10 Reference Standard
  • 詳細內(nèi)容
CBPA0072 
FormatGenomic DNA
DescriptionCYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients.
  
Technical Data 
GeneCYP2D6
Mutation Type 1AA Change: p.S486T
DNA Change: NM_000106.6:c.1457G>C
Chr position (GRCh38): chr22:42126611
Mutation Type 2AA Change: p.P34S
DNA Change: NM_000106.6:c.100C>T
Chr position (GRCh38): chr22:42130692
Allelic Frequency100%
ZygosityHomozygous
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

Figure 1. CYP2D6*10 Reference Standard p.S486T

CBPA0072 p.P34S.png

Figure 2. CYP2D6*10 Reference Standard p.P34S

Storage4°C
Expiry36 months from the date of manufacture

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