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藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73249AXL (Gas6 Dependent)/BaF3

AXL (Gas6 Dependent)/BaF3
名稱 AXL (Gas6 Dependent)/BaF3
型號 CBP73249
報價
特點(diǎn) AXL (Gas6 Dependent)/BaF3,母細(xì)胞:BaF3,AXL (TYRO7) 是一種受體酪氨酸激酶,在各種形式的癌癥中過度表達(dá),包括乳腺癌、前列腺癌、結(jié)腸直腸癌和非小細(xì)胞癌。 AXL 過表達(dá)已被證明可促進(jìn)腫瘤進(jìn)展和轉(zhuǎn)移并降低抗腫瘤免疫反應(yīng),使 AXL 成為抗癌治療的有吸引力的候選者。
  • 詳細(xì)內(nèi)容


CBP73249
I. Introduction

Cell Line Name:

AXL (Gas6 Dependent)/BaF3

Host Cell:

BA/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10% FBS+2 ug/ml puromycin

Mycoplasma Status:

Negative


II.Background
AXL (TYRO7) is a receptor tyrosine kinase that is overexpressed in various forms of cancer, including breast, prostate, colorectal, and non-small cell cancers. AXL overexpression has been shown to encourage tumor progression and metastasis and to decrease the anti-tumor immune response, making AXL an attractive candidate for anticancer therapies.

III. Representative Data

1. Anti-proliferation assay

CBP73249 fig1.png

CBP73249 fig2.jpg


Figure 1. Anti-proliferation assay of three reference compounds on the AXL (Gas6 Dependent)/BaF3 Stable Cell Line.



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