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藥靶細(xì)胞株 > GPCR細(xì)胞株 > CBP71360CXCR1/CHO GPCR細(xì)胞

CXCR1/CHO GPCR細(xì)胞
名稱 CXCR1/CHO GPCR細(xì)胞
型號 CBP71360
報價
特點 CXCR1/CHO
  • 詳細(xì)內(nèi)容
CBP71360
I. Background
CXCR1 (C-X-C Motif Chemokine Receptor 1) is a Protein Coding gene.The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
 
II. Introduction
Host Cell:

CHO

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CXR1 receptor

Transducer:Gi
 
Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

CBP71360 流式.png

Figure 1. Recombinant CXCR1/CHO constitutively expressing  CXCR1.

CBP71360 數(shù)據(jù)圖.png

Figure 2. IL-8 efffect on CHO-CXCR1 clone 6.

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