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藥靶細胞株 > GPCR細胞株 > CBP71364CCR8/CHO GPCR細胞

CCR8/CHO GPCR細胞
名稱 CCR8/CHO GPCR細胞
型號 CBP71364
報價
特點 CCR8/CHO
  • 詳細內容
CBP71364
I. Background

C-C chemokine receptor type 1 (CCR8) is a G protein-coupled receptor member of the CC chemokine subfamily of

receptors. Following interaction with its specific chemokine ligands, like macrophage inflammatory protein 1 alpha

(MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), and monocyte

chemoattractant protein 3 (MCP-3), it triggers the onset of a process known as chemotaxis. GenScript’s human

CCR8-expressing stable subline is guaranteed to function properly in the calcium flux assay.



II. Introduction
Host Cell:

CHO

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CCR8 receptor

Transducer:Gi

Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epithelial
Growth Properties: Adherent

Ⅳ. Representative Data

 COBIOER

Figure 1. Recombinant CCR8/CHO constitutively expressing CCR8.

 COBIOER

Figure 2. CCL1 effect on CCR8/CHO clone 36.





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