名稱(chēng) | FBXW7 p.R505L Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10282 |
報(bào)價(jià) | |
特點(diǎn) | FBXW7 p.R505L Reference Standard |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10282FBXW7 p.R505L Reference Standard 標(biāo)準(zhǔn)品
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CBP10282 | |
Format | Genomic DNA |
Description | FBXW7 R505L lies within the WD repeat 4 of the Fbxw7 protein (UniProt.org). R505L confers a loss of function on Fbxw7, as demonstrated by activation of the NOTCH pathway in cultured cells (PMID: 17646409) and the inability to bind substrates (PMID: 28522751). |
Technical Data | |
DNA Change | c.151ug>T |
AA Change | p.R505L |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000281708 |
Cosmic ID | COSM23000 |
Chr position(GRCh37) | chr4:153247288 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |