名稱 | NRAS p.G12S Reference Standard 標準品 |
型號 | CBP10316 |
報價 | |
特點 | NRAS p.G12S Reference Standard |
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聯(lián)系人:蔣經(jīng)理
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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CBP10316 | |
Format | Genomic DNA |
Description | NRAS G12S is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G12S confers a loss of function on Nras protein as indicated by increased Erk phosphorylation, increased cell preliferation, and is transforming in culture (PMID: 17823240). |
Technical Data | |
DNA Change | c.34G>A |
AA Change | p.G12S |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | ENST00000369535 |
Cosmic ID | COSM563 |
Chr position(GRCh37) | chr1:115258748 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |