名稱 | NRAS p.G13D Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10317 |
報(bào)價(jià) | |
特點(diǎn) | NRAS p.G13D Reference Standard |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10317NRAS p.G13D Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10317 | |
Format | Genomic DNA |
Description | NRAS G13D is a hotspot mutation that lies within a GTP-binding region of the Nras protein (UniProt.org). G13D confers a loss of function on Nras protein as indicated by increased GTP-bound Nras, which leads to activation of downstream pathway signaling in cell culture (PMID: 17517660). |
Technical Data | |
DNA Change | c.38G>A |
AA Change | p.G13D |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | NM_002524.5 |
Cosmic ID | COSM573 |
Chr position(GRCh37) | chr1:115258744 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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