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基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10530TP53 p.E349* Reference Standard 標(biāo)準(zhǔn)品

TP53 p.E349* Reference Standard 標(biāo)準(zhǔn)品
名稱 TP53 p.E349* Reference Standard 標(biāo)準(zhǔn)品
型號(hào) CBP10530
報(bào)價(jià)
特點(diǎn) TP53 p.E349* Reference Standard
  • 詳細(xì)內(nèi)容
 CBP10530
FormatGenomic DNA
DescriptionTP53, tumor protein p53, is a tumor suppressor (PMID: 30562755) and oncogene (PMID: 30577483) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457).
  
Technical Data 
DNA Change:c.1045G>T
AA Changep.E349*
Mutation typeNonsense_Mutation
ZygosityHomozygous
Allelic Frequency100%
TranscriptENST00000269305.4
Cosmic IDCOSM10770
Chr position(GRCh37)chr17:7573982
Buffer:Tris-EDTA
  
Product Information 
Intended UseResearch Use Only
Unit Size1ug
ConcentrationDownload for COA
PuroficationDownload for COA
DNA electrophoresisDownload for COA
Sanger sequencing

CBP10530.png

Storage4℃
Expiry36 months from the date of manufacture

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