名稱 | FGFR3-TACC3 K650N /BaF3細胞株 |
型號 | CBP73377 |
報價 | |
特點 | FGFR3-TACC3 [K650N] /BaF3 |
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藥靶細胞株 > kinase激酶細胞株 > CBP73377FGFR3-TACC3 K650N /BaF3細胞株
- 詳細內(nèi)容
CBP73377 | |
I. Introduction | |
Cell Line Name: | FGFR3-TACC3 [K650N] /BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
FGFR3-TACC3 results from the fusion of FGFR3 and TACC3, demonstrating constitutive kinase activity, transforming activity in culture and ability to drive tumor growth in xenografts (PMID: 25294908, PMID: 22837387). FGFR3-TACC3 has been identified in lung adenocarcinoma and glioblastoma (PMID: 25294908, PMID: 22837387). | |
III. Representative Data | |
1.WB of FGFR3-TACC3 [K650N] /BaF3 | |
2. Sanger of FGFR3-TACC3 [K650N] /BaF3 Figure 2. FGFR3-TACC3 [K650N] /BaF3 K650N Figure 3. FGFR3-TACC3 [K650N] /BaF3 FGFR3-TACC3 | |
3. Anti-proliferation assay Figure 4. CTG Proliferation Assay of BaF3 FGFR3-TACC3 K650N Cells (C3). |