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藥靶細胞株 > kinase激酶細胞株 > CBP73377FGFR3-TACC3 K650N /BaF3細胞株

FGFR3-TACC3 K650N /BaF3細胞株
名稱 FGFR3-TACC3 K650N /BaF3細胞株
型號 CBP73377
報價
特點 FGFR3-TACC3 [K650N] /BaF3
  • 詳細內(nèi)容
CBP73377
I. Introduction

Cell Line Name:

FGFR3-TACC3 [K650N] /BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative


II.Background

FGFR3-TACC3 results from the fusion of FGFR3 and TACC3, demonstrating constitutive kinase activity, transforming activity in culture and ability to drive tumor growth in xenografts (PMID: 25294908, PMID: 22837387). FGFR3-TACC3 has been identified in lung adenocarcinoma and glioblastoma (PMID: 25294908, PMID: 22837387).


III. Representative Data

1.WB of FGFR3-TACC3 [K650N] /BaF3

CBP73377 WB.png

2. Sanger of FGFR3-TACC3 [K650N] /BaF3

CBP73377 sanger-K650N [K650N]FGFR3-TACC3 Baf3.jpg

Figure 2. FGFR3-TACC3 [K650N] /BaF3 K650N

CBP73377 sanger FGFR3-TACC3 BaF3.jpg


Figure 3. FGFR3-TACC3 [K650N] /BaF3 FGFR3-TACC3

3. Anti-proliferation assay

CBP73377 新數(shù)據(jù)圖.png


Figure 4. CTG Proliferation Assay of BaF3 FGFR3-TACC3 K650N Cells (C3).



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