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藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73380KRAS G12C-A59T/BaF3 細(xì)胞株

KRAS G12C-A59T/BaF3 細(xì)胞株
名稱 KRAS G12C-A59T/BaF3 細(xì)胞株
型號 CBP73380
報(bào)價(jià)
特點(diǎn) KRAS G12C-A59T/BaF3
  • 詳細(xì)內(nèi)容
CBP73380
I. Introduction
Cell Line Name:KRAS G12C-A59T/BaF3
Host Cell:Ba/F3
Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Application:Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Freeze Medium:90% FBS+10% DMSO
Complete Culture Medium:RPMI-1640+10%FBS+2ug/ml puromycin
Mycoplasma Status:Negative
 
II.Background

KRAS, KRAS proto-oncogene, GTPase, is a member of the small GTPase superfamily and a key regulator of the MAPK, PI3K/AKT/mTOR pathways (PMID: 23622131). KRAS mutations are identified in a wide range of cancers (PMID: 28666118).

 
III. Representative Data

1. Sanger of  KRAS G12C-A59T/BaF3

CBP73380 sanger-G12C [G12C]Baf3 KRAS G12C+A59T-C13.jpg


Figure 1. KRAS G12C-A59T/BaF3 G12C

CBP73380 sanger-A59T [A59T]Baf3 KRAS G12C+A59T-C13.jpg


Figure 2.  KRAS G12C-A59T/BaF3 A59T

2. Anti-proliferation assay


CBP73380 數(shù)據(jù)圖.jpg

Figure 3. CTG Proliferation Assay of KRAS G12C/A59T BaF3 Cells (C13).

 

 

 

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