名稱 | hCDH6/4T1 |
型號(hào) | CBPG0071 |
報(bào)價(jià) | |
特點(diǎn) | hCDH6/4T1 |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBPG0071hCDH6/4T1
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hCDH6/4T1 hCDH6/4T1 hCDH6/4T1
I. Background | |||
CDH6 (Cadherin 6,鈣粘蛋白 6)是一種 II 型鈣粘附素,是鈣粘附素家族的成員之一。 CDH6 對(duì)于細(xì)胞黏附、胚胎發(fā)育的細(xì)胞識(shí)別、遷移和組織分化、構(gòu)成成體器官都有重要作 用。在胚胎發(fā)育過(guò)程中,參與胚胎腎形態(tài)形成和發(fā)育,驅(qū)動(dòng)腎形態(tài)發(fā)生所需的間充質(zhì)-上皮 分化。CDH6 在甲狀腺腫瘤、膽管癌、骨肉瘤、口腔鱗狀細(xì)胞癌、黑色素瘤、甲狀腺乳頭 狀癌、鼻咽癌、膠質(zhì)瘤、胃癌等腫瘤中起到重要作用。CDH6 還可以作為甘氨酰-tRNA 合 成酶(GRS)的功能性受體在人體內(nèi)部起到抗腫瘤作用。 | |||
II. Introduction | |||
Host Cell: | 4T1 | ||
Expressed gene: | hCDH6 | ||
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) | ||
Freeze Medium: | 90% FBS+10% DMSO | ||
Culture Medium: | RPMI-1640+10%FBS+2μg/ml puromycin | ||
Mycoplasma Testing: | Negative | ||
Storage: | Liquid nitrogen | ||
III. Description of Host Cell Line | |||
Organism: | Mouse | ||
Tissue: | Mammary gland | ||
Morphology: | Epithelial | ||
Growth Properties: | Adherent |
IV. Representative Data | |||
Figure 1. Recombinant hCDH6/4T1 stably expressing CDH6. | |||