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藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73268FGFR2-BICC1/BaF3

FGFR2-BICC1/BaF3
名稱 FGFR2-BICC1/BaF3
型號(hào) CBP73268
報(bào)價(jià)
特點(diǎn) FGFR2-BICC1/BaF3,母細(xì)胞:BaF3,凍存條件:90% FBS+10% DMSO
  • 詳細(xì)內(nèi)容


CBP73268

I. Introduction

Cell Line Name:

FGFR2-BICC1/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:RPMI-1640+10%FBS

Mycoplasma Status:

Negative

II.Background

FGFR2-BICC1 results from the fusion of FGFR2 and BICC1, resulting in the ability to induce oligomerization, Fgfr kinase activity, Mapk signaling and transformation of cells in culture and in animal models (PMID: 23558953, PMID: 24122810, PMID: 28416604). FGFR2-BICC1 has been identified in intrahepatic cholangiocarcinoma (PMID: 25608663, PMID: 31899106).

III. Representative Data

1.WB of  FGFR2-BICC1/BaF3

CBP73268 WB.png


2.Sanger of FGFR2-BICC1/BaF3

CBP73268 sanger.png


3. Anti-proliferation assay

CBP73268 fig.jpg

Figure 3. CTG Proliferation Assay of BaF3 FGFR2-BICC1 Cells (C8).



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