名稱 | ICOS Effector Reporter Cell |
型號(hào) | CBP74063 |
報(bào)價(jià) | ![]() |
特點(diǎn) | ICOS Effector Reporter Cell,凍存條件:90% FBS+10% DMSO; |
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電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74063ICOS Effector Reporter Cell

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ICOS Effector Reporter Cell
CBP74063 | |
I. Background | |
ICOS is a costimulatory molecule of the CD28 cell surface receptor superfamily that is expressed on activated T-cells. ICOS is involved in T-cell responses upon binding with its ligand, ICOSL (also known as B7-H2, CD275), which is normally expressed on B-cells, dendritic cells and monocytes. | |
II. Description | |
ICOS expression confers an activated phenotype and a strong suppressive capacity to intra-tumoral regulatory T-cells. The ICOS/ICOSL pathway is a key target for cancer immunotherapy. | |
III. Introduction | |
Expressed gene: | ICOS |
Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Synonym(s): | T-cell costimulator, CD278 |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | RPMI-1640+10%FBS+800ug/ml hygromycin+10ug/ml blasticidin |
Mycoplasma Testing: | Negative |
Storage: | Liquid nitrogen |
Application(s): | Functional(Report Gene) Assay |
IV. Representative Data | |
Figure 1. Dose response of Anti-lCOS Ab in ICOS Effector Reporter Cells(C5). | |