名稱 | PIK3CA p.E545K Reference Standard 標準品 |
型號 | CBP10322 |
報價 | |
特點 | PIK3CA p.E545K Reference Standard |
產品搜索
相關文章
聯(lián)系我們
聯(lián)系人:蔣經理
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
產品展示 / PRODUCTS
- 詳細內容
" _ue_custom_node_="true">
CBP10322 | |
Format | Genomic DNA |
Description | PIK3CA E545K is a hotspot mutation that lies within the PIK helical domain of the Pik3ca protein (UniProt.org). E545K results in increased phosphorylation of Akt and Mek1/2, growth factor-independent cell survival, and is transforming in culture (PMID: 26627007, PMID: 29533785). |
Technical Data | |
DNA Change | c.1633G>A |
AA Change | p.E545K |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | NM_006218.1 |
Cosmic ID | COSM763 |
Chr position(GRCh37) | chr3:178936091 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |