名稱(chēng) | PIK3CA p.R88Q Reference Standard 標(biāo)準(zhǔn)品 |
型號(hào) | CBP10331 |
報(bào)價(jià) | |
特點(diǎn) | PIK3CA p.R88Q Reference Standard |
產(chǎn)品搜索
產(chǎn)品分類(lèi)
相關(guān)文章
聯(lián)系我們
聯(lián)系人:蔣經(jīng)理
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10331PIK3CA p.R88Q Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10331 | |
Format | Genomic DNA |
Description | PIK3CA R88Q lies within the PI3K-ABD domain of the Pik3ca protein (UniProt.org). R88Q confers a gain of function to the Pik3ca protein as indicated by increased phosphorylation of downstream targets Akt and S6 (PMID: 18829572) and demonstrates increased transformation ability in two different cell lines, as compared to wild-type Pik3ca (PMID: 29533785). |
Technical Data | |
DNA Change | c.263G>A |
AA Change | p.R88Q |
Mutation type | Substitution - Missense |
Zygosity | Heterozygous |
Allelic Frequency | 50.00% |
Transcript | NM_006218.1 |
Cosmic ID | COSM746 |
Chr position(GRCh37) | chr3:178916876 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
" _ue_custom_node_="true">