名稱 | PTEN p.R130Afs*51 Reference Standard 標(biāo)準(zhǔn)品 |
型號 | CBP10464 |
報(bào)價(jià) | |
特點(diǎn) | PTEN p.R130Afs*51 Reference Standard |
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10464PTEN p.R130Afs*51 Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10464 | |
Gene | PTEN |
Description | PTEN, phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN, is a tumor suppressor (PMID: 30562755) with roles in the cell cycle, growth, DNA repair, cell survival and regulation of the Akt-mTOR pathway (PMID: 24656806, PMID: 30145641). PTEN germline mutations are common in Cowden syndrome (PMID: 30562755) and PTEN somatic alterations resulting in loss of function have been found in many types of cancer including, but not limited to endometrial (PMID: 30142194), melanoma (PMID: 30148988), and prostate (PMID: 18767981, PMID: 30153654). |
Technical Data | |
DNA Change | c.386_387insCGCC |
AA Change | p.R130Afs*51 |
Mutation type | Frame_Shift_Ins |
Zygosity | Homozygous |
Allelic Frequency | 100.00% |
Transcript | ENST00000371953.3 |
Cosmic ID | N/A |
Chr position(GRCh37) | chr10:89692902_89692903 |
Buffer | Tris-EDTA |
Product Information | |
Intended Use | Research Use Only |
Unit Size | 1ug |
Concentration | Download for COA |
Purofication | Download for COA |
DNA electrophoresis | Download for COA |
Sanger sequencing | |
Storage | 4℃ |
Expiry | 36 months from the date of manufacture |
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