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藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74173hIL18 Effector Reporter Cell

hIL18 Effector Reporter Cell
名稱 hIL18 Effector Reporter Cell
型號(hào) CBP74173
報(bào)價(jià)
特點(diǎn) hIL18 Effector Reporter Cell
  • 詳細(xì)內(nèi)容
CBP74173
I. Background
Interleukin-18 (IL18, also known as interferon-gamma inducing factor or IGIF) is a cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. Its biological activity is pleiotropic and it has been shown to induce interferon-gamma production in KG-1 cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production in B cells.
 
II.Introduction
Expressed gene:hIL18
Stability:32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Synonym(s):IL18; IGIF; IL-18; IL-1g; IL1F4; interleukin 18
Freeze Medium:90% FBS+10%DMSO
Culture Medium:RPMI-1640+10%FBS+1ug/ml puromycin+800ug/ml hygromycin+10ug/ml blasticidin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
Application(s):Functional(Report Gene) Assay
 
 
III. Representative Data

CBP74173-1.jpg

Figure 1.Dose Response of Recombinant IL-18 in IL-18 Effector Reporter Cells(C12).

CBP74173-2.jpg

Figure 2.Inhibition of hIL18-Induced Reporter Activity By Recombinant Human IL18 BP Protein in hIL18 Effector Reporter Cells(C12).

 

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