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藥靶細胞株 > 腫瘤免疫細胞株 > CBPG0001hPD-L1/MC38

hPD-L1/MC38
名稱 hPD-L1/MC38
型號 CBPG0001
報價
特點 hPD-L1/MC38
  • 詳細內容
CBPG0001
I. Background
The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. The PD-1 ligands are found on most cancers, and PD-1:PD-L1/2 interaction inhibits T cell activity and allows cancer cells to escape immune surveillance. The PD-1:PD-L1/2 pathway is also involved in regulating autoimmune responses, making these proteins promising therapeutic targets for a number of cancers, as well as multiple sclerosis, arthritis, lupus, and type I diabetes.
II. Introduction
Host Cell:MC38
Expressed gene:hPD-L1
Stability:32 passages
Freeze Medium:90% FBS+10% DMSO
Culture Medium:DMEM+10%FBS+5ug/ml blasticidin
Mycoplasma Testing:Negative
Storage:Liquid nitrogen
III. Description of Host Cell Line
Organism:Mouse
Tissue:Colon
Morphology: Epitheloid cell
Growth Properties: Adherent
IV. Representative Data

CBPG0001.png

Figure 1. Recombinant hPD-L1/MC38 stably expressing hPD-L1.



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