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藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73331CD74-ROS1/BaF3 kinase細(xì)胞株

CD74-ROS1/BaF3 kinase細(xì)胞株
名稱 CD74-ROS1/BaF3 kinase細(xì)胞株
型號(hào) CBP73331
報(bào)價(jià)
特點(diǎn) CD74-ROS1/BaF3
  • 詳細(xì)內(nèi)容



CBP73331

I. Introduction

Cell Line Name：

CD74-ROS1/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative


II.Background

CD74, CD74 molecule, encodes for a type II integral membrane glycoprotein that acts as an MHC class II chaperone and plays a role in the signal transduction of pathways related to cell survival, proliferation (PMID: 16484589, PMID: 27058619), and the immune system (PMID: 30191677). Overexpression of Cd74 has been observed in gastrointestinal cancer (PMID: 21228923) and hematological cancers (PMID: 30191677), and CD74-ROS1 and CD74-NRG1 fusions have been identified in lung cancer (PMID: 22215748, PMID: 31027745, PMID: 29169524).


III. Representative Data

1. Sanger of  CD74-ROS1/BaF3



2. Anti-proliferation assay

Figure 2. CTG Proliferation Assay of BaF3 CD74-ROS1 Cells (C1).




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