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藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73341EML4-ALK V1 G1269A/BaF3

EML4-ALK V1 G1269A/BaF3
名稱 EML4-ALK V1 G1269A/BaF3
型號(hào) CBP73341
報(bào)價(jià)
特點(diǎn) EML4-ALK V1 [G1269A]/BaF3
  • 詳細(xì)內(nèi)容


CBP73341
I. Introduction

Cell Line Name:

EML4-ALK V1 [G1269A]/BaF3

Host Cell:

Ba/F3

Stability:16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)

Application:

Anti-proliferation assay and PD assay

Freeze Medium:

90% FBS+10% DMSO

Complete Culture Medium:

RPMI-1640+10%FBS

Mycoplasma Status:

Negative

II.Background

EML4-ALK results from the fusion of EML4 and ALK, resulting in constitutive kinase activity, transformation in cultured cells, and tumor activity in mouse models (PMID: 19064915, PMID: 17625570). EML4-ALK fusions have been associated with non-small cell lung cancer (PMID: 26755435).

III. Representative Data

1.WB of EML4-ALK V1 [G1269A]/BaF3


2. Sanger of EML4-ALK V1 [G1269A]/BaF3

Figure 1. EML4-ALK V1 [G1269A]/BaF3 Fusion

Figure 2. EML4-ALK V1 [G1269A]/BaF3 G1269A

3. Anti-proliferation assay

Figure 3. CTG Proliferation Assay of BaF3 EML4-ALK V1 [G1269A] (C1).



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