名稱 | PDGFRA V658A/BaF3 細胞株 |
型號 | CBP73379 |
報價 | |
特點 | PDGFRA V658A/BaF3 |
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聯(lián)系人:蔣經(jīng)理
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Email: zhangxiangwen@cobioer.com
電話:4008750250
號碼:
手機:18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
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藥靶細胞株 > kinase激酶細胞株 > CBP73379PDGFRA V658A/BaF3 細胞株
- 詳細內(nèi)容
CBP73379 | |
I. Introduction | |
Cell Line Name: | PDGFRA V658A/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS+200ng/ml PDGF-BB |
Mycoplasma Status: | Negative |
II.Background | |
PDGFRA, platelet-derived growth factor receptor alpha, is a receptor tyrosine kinase that activates PI3K/Akt, RAS/MAPK, and JAK/STAT pathways to promote cell proliferation and survival (PMID: 21605429). PDGFRA mutations have been detected in melanoma, AML, peripheral nerve sheath tumors, sarcoma, and neuroendocrine carcinomas (PMID: 23752188, PMID: 20685895), several fusions have also been reported (PMID: 22432087, PMID: 26276769), and amplification has been observed in glioblastoma (PMID: 23438035). | |
III. Representative Data | |
1.Sanger of PDGFRA V658A/BaF3 Figure 1. PDGFRA V658A/BaF3 V658A |